Service
Our group provides proteomics analyses based on mass spectrometry detection. We primarily support research groups within IOCB Prague, but we are also open to collaborations with external groups within our available capacity. In addition, we offer commercial services to both academic and industrial partners. For detailed information about our services, please visit our intraweb page (accessible to UOCHB employees only), or contact us directly.
Bottom-up proteomics
- Identification and quantification of proteins on a proteome level
- Characterization of post-translational modifications
Top-down proteomics
- Denaturing intact mass of proteins / oligonucleotides
- Native mass of proteins / oligonucleotides / protein and protein-ligand complexes / other biomolecules
Structural proteomics
- HDX-MS (Hydrogen/Deuterium Exchange Mass Spectrometry)
- XL-MS (Cross-linking Mass Spectrometry)